High Protein Italian Beef Pasta Bake

Featured in: Weeknight Dinners

This comforting baked pasta dish combines extra-lean ground beef with whole wheat pasta, colorful vegetables, and a rich tomato sauce. The golden melted mozzarella and Parmesan topping creates a crispy, cheesy layer that families love. Ready in under an hour, this high-protein meal yields six generous servings and reheats beautifully for lunches throughout the week.

Updated on Sun, 25 Jan 2026 14:01:56 GMT
A close-up of High Protein Italian Beef and Pasta Bake with melted mozzarella and Parmesan bubbling over golden, savory beef and vegetable sauce. Pin It
A close-up of High Protein Italian Beef and Pasta Bake with melted mozzarella and Parmesan bubbling over golden, savory beef and vegetable sauce. | urbanspatula.com

This High Protein Italian Beef and Pasta Bake is a hearty, pizza-inspired main dish that perfectly balances comfort and nutrition. With a total time of 50 minutes and an easy difficulty rating, it is an ideal Italian-American meal for busy weeknights or a successful meal prep session. By combining extra-lean ground beef, whole wheat pasta, and a variety of vegetables, this recipe provides a satisfying high-protein option that is lower in calories without sacrificing flavor.

A close-up of High Protein Italian Beef and Pasta Bake with melted mozzarella and Parmesan bubbling over golden, savory beef and vegetable sauce. Pin It
A close-up of High Protein Italian Beef and Pasta Bake with melted mozzarella and Parmesan bubbling over golden, savory beef and vegetable sauce. | urbanspatula.com

The secret to this bake is the savory blend of crushed tomatoes and tomato paste, seasoned with oregano, basil, and a hint of chili flakes. The result is a rich, savory sauce that coats every piece of whole wheat pasta. Topped with a blend of mozzarella and Parmesan cheese, this dish yields 6 hearty servings that are as delicious as they are nutritious.

Ingredients

  • Pasta: 300 g (10.5 oz) whole wheat penne or rotini
  • Beef & Vegetables: 450 g (1 lb) extra-lean ground beef, 1 medium onion (diced), 2 cloves garlic (minced), 1 red bell pepper (diced), 100 g (3.5 oz) mushrooms (sliced), 100 g (3.5 oz) baby spinach
  • Sauce: 700 ml (24 oz) canned crushed tomatoes, 2 tbsp tomato paste, 1 tsp dried oregano, 1 tsp dried basil, ½ tsp chili flakes (optional), Salt and freshly ground black pepper to taste
  • Cheese & Toppings: 150 g (5 oz) part-skim mozzarella cheese (shredded), 30 g (1 oz) grated Parmesan cheese, 30 g (1 oz) turkey pepperoni slices (optional, for pizza flavor), Fresh basil for garnish (optional)
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Instructions

Step 1
Preheat oven to 200°C (400°F).
Step 2
Cook pasta in a large pot of boiling salted water until al dente. Drain and set aside.
Step 3
In a large nonstick skillet over medium heat, cook the ground beef until browned, breaking it up as it cooks. Drain excess fat if needed.
Step 4
Add onion, garlic, bell pepper, and mushrooms to the skillet. Sauté for 5–7 minutes until softened.
Step 5
Stir in spinach and cook until wilted, about 1 minute.
Step 6
Add crushed tomatoes, tomato paste, oregano, basil, chili flakes, salt, and pepper. Simmer for 5 minutes, allowing flavors to meld.
Step 7
Combine the cooked pasta with the beef and vegetable sauce mixture.
Step 8
Transfer the mixture to a lightly greased 23x33 cm (9x13 inch) baking dish.
Step 9
Sprinkle mozzarella and Parmesan evenly over the top. Arrange turkey pepperoni slices if using.
Step 10
Bake for 20 minutes, until cheese is melted and bubbly.
Step 11
Garnish with fresh basil before serving, if desired.

Zusatztipps für die Zubereitung

To successfully prepare this bake, ensure you have a large pot for the pasta, a large nonstick skillet for the beef mixture, and a 23x33 cm (9x13 inch) baking dish. Using a cheese grater for the Parmesan will help it melt more evenly over the beef and vegetable sauce. Always make sure to drain any excess fat from the beef to keep the calorie count lower.

Varianten und Anpassungen

For extra protein, stir 200 g (7 oz) low-fat cottage cheese or ricotta into the pasta mixture before baking. You can also use chickpea or lentil pasta for a gluten-free, even higher protein option. For a Mediterranean flavor twist, consider adding black olives or roasted zucchini to the vegetable mix.

Serviervorschläge

This hearty Italian beef and pasta dish is best served with a crisp green salad on the side to provide a fresh and crunchy contrast to the savory, melty pasta bake.

Serving suggestion for High Protein Italian Beef and Pasta Bake in a white casserole dish, garnished with fresh basil and turkey pepperoni. Pin It
Serving suggestion for High Protein Italian Beef and Pasta Bake in a white casserole dish, garnished with fresh basil and turkey pepperoni. | urbanspatula.com

Please be aware that this dish contains wheat and milk, and may contain soy depending on the specific processed meat or cheese used. Always check ingredient labels to confirm allergen status. At 370 calories and 33g of protein per serving, this is a nutritious meal the whole family will love.

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Questions & Answers

Can I make this dish ahead of time?

Absolutely. Assemble the entire dish up to 24 hours in advance, cover tightly, and refrigerate. Add 5-10 minutes to the baking time if baking cold from the refrigerator.

What pasta shapes work best?

Penne or rotini are ideal because their ridges and curves hold the sauce well. Macaroni or fusilli would also work nicely. Avoid long strands like spaghetti.

Can I freeze leftovers?

Yes, portion the cooled bake into airtight containers and freeze for up to 3 months. Thaw overnight in the refrigerator and reheat at 180°C (350°F) until hot throughout.

How can I increase the protein content?

Stir in 200 g of low-fat cottage cheese or ricotta before baking. Alternatively, use legume-based pasta like chickpea or lentil pasta instead of whole wheat.

What vegetables can I add or substitute?

Try diced zucchini, eggplant, or black olives for Mediterranean flair. Chopped kale or Swiss chard can replace spinach. Adjust cooking times as needed for harder vegetables.

Is this suitable for gluten-free diets?

Simply substitute the whole wheat pasta with your favorite gluten-free pasta. Chickpea or lentil pasta are excellent high-protein alternatives that also happen to be gluten-free.

High Protein Italian Beef Pasta Bake

Hearty baked pasta with lean beef, vegetables, and melty cheese topping.

Prep Time
20 minutes
Cook Time
30 minutes
Overall Time
50 minutes
Created by Carter Phillips


Skill Level Easy

Cuisine Italian-American

Portions 6 Serving Size

Diet Preferences None specified

What You’ll Need

Pasta

01 10.5 oz whole wheat penne or rotini pasta

Beef & Vegetables

01 1 lb extra-lean ground beef
02 1 medium onion, diced
03 2 cloves garlic, minced
04 1 red bell pepper, diced
05 3.5 oz mushrooms, sliced
06 3.5 oz baby spinach

Sauce

01 24 fl oz canned crushed tomatoes
02 2 tablespoons tomato paste
03 1 teaspoon dried oregano
04 1 teaspoon dried basil
05 0.5 teaspoon chili flakes, optional
06 Salt and freshly ground black pepper to taste

Cheese & Toppings

01 5 oz part-skim mozzarella cheese, shredded
02 1 oz grated Parmesan cheese
03 1 oz turkey pepperoni slices, optional
04 Fresh basil for garnish, optional

How-To Steps

Step 01

Prepare oven: Preheat oven to 400°F.

Step 02

Cook pasta: Cook pasta in a large pot of boiling salted water until al dente. Drain and set aside.

Step 03

Brown ground beef: In a large nonstick skillet over medium heat, cook the ground beef until browned, breaking it up as it cooks. Drain excess fat if needed.

Step 04

Sauté vegetables: Add onion, garlic, bell pepper, and mushrooms to the skillet. Sauté for 5 to 7 minutes until softened.

Step 05

Wilt spinach: Stir in spinach and cook until wilted, about 1 minute.

Step 06

Prepare sauce: Add crushed tomatoes, tomato paste, oregano, basil, chili flakes, salt, and pepper. Simmer for 5 minutes to allow flavors to meld.

Step 07

Combine pasta and sauce: Combine the cooked pasta with the beef and vegetable sauce mixture.

Step 08

Transfer to baking dish: Transfer the mixture to a lightly greased 9x13 inch baking dish.

Step 09

Add cheese topping: Sprinkle mozzarella and Parmesan evenly over the top. Arrange turkey pepperoni slices if using.

Step 10

Bake: Bake for 20 minutes, until cheese is melted and bubbly.

Step 11

Garnish and serve: Garnish with fresh basil before serving if desired.

Tools You’ll Need

  • Large pot
  • Large nonstick skillet
  • 9x13 inch baking dish
  • Mixing spoon
  • Cheese grater

Allergy Warnings

Review every ingredient for allergens and ask a professional if you’re unsure.
  • Contains wheat from pasta
  • Contains milk from cheese and optional cottage cheese or ricotta
  • May contain soy from processed meat or cheese labels

Nutrition Info (for each serving)

These nutrition details are for reference and don’t replace medical guidance.
  • Energy: 370
  • Fats: 11 g
  • Carbohydrates: 37 g
  • Proteins: 33 g