Spinach Artichoke Grilled Cheese

Featured in: Weeknight Dinners

Transform classic grilled cheese with a creamy spinach and artichoke filling. Sauté fresh spinach and artichoke hearts, blend with mozzarella, cream cheese, and Parmesan, then spread between buttered sourdough slices. Cook until golden and melted on both sides.

This vegetarian sandwich combines gourmet flavors with simple preparation, taking just 25 minutes from start to finish. Perfect served with tomato soup for an elevated lunch or dinner experience.

Updated on Sun, 18 Jan 2026 14:51:00 GMT
Creamy spinach artichoke grilled cheese with melted mozzarella on buttery, golden sourdough slices for a comforting lunch. Pin It
Creamy spinach artichoke grilled cheese with melted mozzarella on buttery, golden sourdough slices for a comforting lunch. | urbanspatula.com

My neighbor Sarah knocked on my door one rainy Tuesday with a jar of marinated artichokes and a wild idea. She'd been experimenting with stuffed breads all week, and this spinach artichoke combo had become her obsession. We stood in my kitchen, rain drumming on the window, and pressed these sandwiches together while laughing about how we'd turned a party dip into dinner. The cheese stretched between the halves like we'd discovered something sacred.

I made these for my brother when he came over to help me assemble a bookshelf. He's the kind of guy who survives on protein bars and takeout, but he stopped mid-bite, looked at me, and asked if I'd opened a cafe without telling him. We ended up eating four sandwiches between us and never finished the bookshelf. He still texts me asking when I'm making them again, and the shelf is still only half-built in my hallway.

Ingredients

  • Shredded mozzarella cheese: This is your melt factor, the cheese that stretches and binds everything into that pull-apart moment you want in every bite.
  • Cream cheese, softened: It makes the filling creamy and spreadable instead of clumpy, so leave it out on the counter for twenty minutes before you start.
  • Grated Parmesan cheese: The salty, nutty backbone that keeps this from tasting flat or one-note.
  • Unsalted butter, softened: Spread it on the outside of the bread so it crisps up golden without burning.
  • Fresh spinach, chopped: Wilts down to almost nothing, so don't worry if the raw pile looks huge.
  • Canned or jarred artichoke hearts, drained and chopped: Make sure you squeeze out the extra liquid or your filling will turn soupy.
  • Small garlic clove, minced: Just one is enough to add warmth without overpowering the creamy cheese.
  • Sourdough bread: The slight tang plays beautifully with the richness, and it holds up to the weight of the filling.
  • Salt, black pepper, and red pepper flakes: Season to your mood, the red flakes add a little kick that sneaks up on you.

Instructions

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Wilt the spinach:
Toss the spinach into a medium skillet over medium heat with just a splash of water. It'll shrink fast, in about a minute or two. Drain it well and press out the extra moisture with a spoon, or your sandwich will get soggy.
Mix the filling:
Combine the wilted spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, garlic, salt, pepper, and red pepper flakes in a bowl. Stir it all together until it's creamy and every bit of cheese is coated with greens.
Assemble the sandwiches:
Spread the spinach-artichoke mixture generously onto two slices of sourdough. Top with the other slices and press down gently so they stick together.
Butter the outsides:
Spread softened butter evenly on the outer sides of each sandwich. This is what turns the bread golden and crisp, so don't skip it or go too thin.
Grill until golden:
Heat a large nonstick skillet or griddle over medium heat and place the sandwiches in. Cook for three to four minutes per side, pressing gently with a spatula, until the bread is deeply golden and the cheese inside is melted and gooey.
Slice and serve:
Remove from heat, cut each sandwich in half, and serve immediately while the cheese is still stretchy.
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Two golden spinach artichoke grilled cheese sandwiches served hot, oozing cheese, perfect alongside a bowl of tomato soup. Pin It
Two golden spinach artichoke grilled cheese sandwiches served hot, oozing cheese, perfect alongside a bowl of tomato soup. | urbanspatula.com

One Saturday morning, I made these for my mom after she'd been up all night helping me paint my kitchen. She sat at the table in her paint-splattered shirt, took a bite, and said it tasted like something you'd order at a bistro and pay fifteen dollars for. That's when I realized this sandwich had become my secret weapon for making ordinary moments feel a little more special.

Choosing Your Bread

Sourdough is my go-to because the slight tang balances the richness of the cheese, and it crisps up beautifully without getting tough. But I've made these with whole wheat when I wanted something heartier, and even a good multigrain when I was trying to sneak in some extra fiber. Just avoid anything too soft or thin, because the filling is heavy and you need bread with some structure to hold it all in without falling apart.

Making It Your Own

I've added a handful of chopped fresh basil when I had some wilting in the fridge, and it brought a bright, summery note that made the whole thing feel lighter. A sprinkle of smoked paprika in the filling gives it a subtle depth that people can't quite place but always ask about. You could even toss in some sun-dried tomatoes if you want a little sweetness and chew, or swap the mozzarella for fontina if you're feeling fancy.

Serving Suggestions

These sandwiches are perfect with a bowl of tomato soup, the classic pairing that never gets old. I've also served them alongside a simple green salad with lemon vinaigrette when I wanted something lighter to cut through the richness. If you're feeding a crowd, slice them into quarters and serve them as appetizers, they disappear fast.

  • Pair with a crisp white wine or iced tea for an easy lunch.
  • Add a handful of arugula inside the sandwich for a peppery bite.
  • Store leftover filling in the fridge for up to three days and use it as a dip with crackers.
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Close-up of a spinach artichoke grilled cheese, crispy sourdough crust and vibrant green filling on a rustic plate. Pin It
Close-up of a spinach artichoke grilled cheese, crispy sourdough crust and vibrant green filling on a rustic plate. | urbanspatula.com

This sandwich has become my answer to lazy Sundays, surprise guests, and those nights when I want comfort without the fuss. I hope it shows up in your kitchen the same way it did in mine, turning simple ingredients into something that feels like a small celebration.

Questions & Answers

Can I prepare the spinach artichoke filling in advance?

Yes, you can prepare the filling up to 2 days ahead and store it in an airtight container in the refrigerator. Simply reheat gently before assembling your sandwiches.

What bread alternatives work best?

While sourdough provides the best tang and texture, whole wheat, multigrain, or ciabatta bread are excellent substitutes. Avoid soft breads that may fall apart during cooking.

How do I prevent the filling from leaking out?

Drain the artichoke hearts thoroughly and squeeze excess moisture from the cooked spinach. Spread the filling evenly and avoid overfilling. Press gently while cooking to help seal the sandwich.

Can I add meat to this sandwich?

Absolutely. Crispy bacon, prosciutto, or diced ham pair wonderfully with the spinach and artichoke filling. Add about 2 slices per sandwich.

What temperature should I cook at?

Medium heat is ideal for achieving golden-brown bread without burning the exterior while allowing the cheese to melt completely. Adjust heat if browning too quickly.

Are there flavor variations I can try?

Try adding fresh basil, sun-dried tomatoes, roasted garlic, smoked paprika, or red pepper flakes for extra depth. A touch of balsamic vinegar or pesto also enhances the filling beautifully.

Spinach Artichoke Grilled Cheese

Gourmet grilled cheese featuring creamy spinach and artichoke filling nestled between crisp, golden sourdough slices.

Prep Time
15 minutes
Cook Time
10 minutes
Overall Time
25 minutes
Created by Carter Phillips


Skill Level Easy

Cuisine American

Portions 2 Serving Size

Diet Preferences Meat-Free

What You’ll Need

Dairy

01 1 cup shredded mozzarella cheese
02 1/2 cup cream cheese, softened
03 1/4 cup grated Parmesan cheese
04 2 tablespoons unsalted butter, softened

Vegetables

01 1 cup fresh spinach, chopped
02 1/2 cup canned or jarred artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Bread

01 4 slices sourdough bread

Seasonings

01 1/4 teaspoon salt
02 1/8 teaspoon freshly ground black pepper
03 Pinch of red pepper flakes, optional

How-To Steps

Step 01

Prepare the spinach: In a medium skillet over medium heat, add spinach with a splash of water. Sauté for 1-2 minutes until wilted, then drain excess moisture.

Step 02

Combine filling ingredients: In a bowl, combine sautéed spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, garlic, salt, pepper, and red pepper flakes if using. Mix until well blended.

Step 03

Assemble sandwiches: Spread the spinach-artichoke mixture evenly onto two slices of sourdough bread. Top with the remaining bread slices to form sandwiches.

Step 04

Butter the bread: Butter the exterior surfaces of all bread slices on both sandwiches.

Step 05

Cook until golden: Heat a large nonstick skillet or griddle over medium heat. Place sandwiches in the skillet and cook for 3-4 minutes per side, pressing gently, until bread is golden brown and cheese is melted.

Step 06

Serve: Remove from heat, slice sandwiches in half diagonally, and serve immediately.

Tools You’ll Need

  • Medium skillet
  • Mixing bowl
  • Spatula
  • Nonstick skillet or griddle
  • Knife

Allergy Warnings

Review every ingredient for allergens and ask a professional if you’re unsure.
  • Contains milk from cheese and butter
  • Contains wheat from sourdough bread
  • May contain traces of soy or tree nuts depending on bread and cheese brands

Nutrition Info (for each serving)

These nutrition details are for reference and don’t replace medical guidance.
  • Energy: 430
  • Fats: 24 g
  • Carbohydrates: 39 g
  • Proteins: 16 g